mongoDB does a huge collection affects the preformance of other collections?

mongoDB does a huge collection affects the preformance of other collections?

In my application I'm about to save some files on the DB. I've seen the
debate whether to save on the filesystem \ db and chose to save the files
on the database.
my database for the project is mongoDB.
I would like to know if i have lets say 100 collections in my mongoDB, and
exactly one of them is extremely big. will i see a performance impact when
i work on the other (less large) collections?
if So should i separate this collection from the other collections ?
(create another DB for this huge collection alone)?
Does my-sql suffer from the same effect?
thanks.